Abstract

The aim of the current work was to elucidate if there is a connection between stress-induced decrease in coeliacomesenteric artery blood flow (i.e. gastrointestinal blood flow; GBF) and disruption of the intestinal primary barrier in rainbow trout Oncorhynchus mykiss. Upon initiation of a 15 min acute chasing stress, the GBF decreased instantly by c. 92%. The GBF then slowly increased and reached c. 28% of resting values at the end of the stress protocol. After the stress was ceased, the GBF slowly increased and returned to resting values within c. 45 min. Intestinal permeability assessment in an Ussing-chambers set-up revealed impaired intestinal barrier function 24 h after stress. When the stress-induced GBF reduction was mimicked by an experimental occlusion of the coeliacomesenteric artery for 15 min followed by 24 h recovery, no effect on intestinal barrier function was observed. These results suggest that no direct causal relationship can be found between the GBF reduction and development of intestinal barrier dysfunction following periods of acute stress in this species of fish.

Keywords

acute stress; barrier function; gastrointestinal blood flow; occlusion; salmonids; stress response

Published in

Journal of Fish Biology
2018, Volume: 93, number: 3, pages: 519-527
Publisher: WILEY

SLU Authors

• Gräns, Albin

  • Department of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences
    

• Brijs, Jeroen

  • Department of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences
    

• Berg, Lotta

  • Department of Applied Animal Science and Welfare, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Fish and Aquacultural Science


Publication identifier

DOI: https://doi.org/10.1111/jfb.13658

Permanent link to this page (URI)

https://res.slu.se/id/publ/96705