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Review article - Peer-reviewed, 1995

Evaluation of certain veterinary drug residues in food : forty-second report of the Joint FAO/WHO Expert Committee on Food Additives

ABIOLA, FA; APPELGREN, LE; ARNOLD, D; BOISSEAU, J; CUERPO, L; ELLIS, R; FURROW, RD; MCLEAN, JG; PINTER, A; PUGH, DM; RICO, A; SINHASENI, P; WELLS, R; YNDESTAD, M; CHAMBERLAIN, P; FUCHS, R; HEITZMAN, RJ; HERRMAN, JL; KIDD, ARM; LIVINGSTON, RC;
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Abstract

This report presents the conclusions of a Joint FAO/WHO Expert Committee convened to evaluate the safety of residues of certain veterinary drugs in edible animal products, with a view to promoting human food safety and harmonization in international trade. In the first part of the report, principles for evaluating the safety of residues of veterinary drugs in food and for establishing Acceptable Daily Intakes and Maximum Residue Limits for such residues are elaborated. In particular, risk assessment procedures use by the Committee, the application of safety factors, the assessment of microbiological risk due to residues of antimicrobial drugs in food, and the problem of residues at the injection site are discussed. The information required by the Committee in investigating the human food safety of residues of veterinary drugs is also listed. A summary follows of the Committee's evaluations and toxicological and residue data on an anthelminthic (levamisole), five antimicrobial agents (chloramphenicol, flumequine, olaquindox, spectinomycin and sulfadimidine), an antiprotozoal agent (ronidazole), a glucocorticosteroid (dexamethasone) and a trypanocide (diminazene). For each drug, an Acceptable Daily Intake and Maximum Residue Limits for certain edible animal products are recommended, as appropriate, or deficiencies in the available data are identified and requirements for further information specified.

Published in

Technical Report Series- World Health Organization
1995, Volume: 851, pages: 1-41
Publisher: WORLD HEALTH ORGANIZATION

      SLU Authors

    • Appelgren, Lars-Erik

      • Department of Pharmacology and Toxicology, Swedish University of Agricultural Sciences

    UKÄ Subject classification

    Food Science
    Pharmacology and Toxicology

    Permanent link to this page (URI)

    https://res.slu.se/id/publ/97421