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Research article2006Peer reviewed

Modelling ECT effects by connectivity changes in cortical neural networks

Gu, Yuqiao; Halnes, Geir; Liljenström, Hans; von, Rosen Dietrich; Wahlund, Björn; Liang, Hualou

Abstract

Biomathematical methods were applied to investigate how cortical neurodynamics depends on network connectivity. In particular, we study changes in the EEG pattern of depressed patients, following electroconvulsive therapy (ECT). The aim is to gain a better understanding of the neural mechanisms responsible for these changes, which include clear phase shifts in the EEG dynamics. This understanding is intended to provide clinical guidance in predicting ECT dose and response in depressed patients

Keywords

EEG; Clinical data; Neurodynamics; Neo-cortical network; Fitzhugh–Nagumo neurons

Published in

Neurocomputing
2006, Volume: 69, pages: 1341-1347
Publisher: Elsevier

      SLU Authors

    • Halnes, Geir

      • Department of Biometry and Engineering, Swedish University of Agricultural Sciences

      • Liljenström, Hans

        • Department of Biometry and Engineering, Swedish University of Agricultural Sciences

        • von Rosen, Dietrich

          • Department of Biometry and Engineering, Swedish University of Agricultural Sciences

        UKÄ Subject classification

        Neurology

        Publication identifier

        DOI: https://doi.org/10.1016/j.neucom.2005.12.104

        Permanent link to this page (URI)

        https://res.slu.se/id/publ/9744