Abstract
Background: The occurrence of small vessel arteriosclerosis in the myocardium, kidney, and lung in dogs with naturally occurring rnyxomatous mitral valve disease has not been previously investigated systematically. Methods: Twenty-one dogs with naturally occurring congestive heart failure and 21 age-matched, sex-matched, and weight-matched control dogs underwent extensive pathological and histopathological examination. Morphometry and scoring of tissue sections were used to measure arterial narrowing and fibrosis in the myocardium, kidney, and lung; and intimal thickness and plaque formation in the aorta and pulmonary artery. Results: Dogs with congestive heart failure had significantly more arterial narrowing in the left ventricle (P
Keywords
Valve disease; coronary circulation; coronary disease; models
Published in
Cardiovascular Pathology
2006, volume: 15, number: 4, pages: 185-193
Publisher: ELSEVIER SCIENCE INC
UKÄ Subject classification
Veterinary Science
Animal and Dairy Science
Publication identifier
- DOI: https://doi.org/10.1016/j.carpath.2006.04.003
Permanent link to this page (URI)
https://res.slu.se/id/publ/9753