A multivariate NIR study of skin alterations in diabetic patients as compared to control subjects

Abstract

A group of 15 diabetic persons with different degrees of diabetes complications, including skin changes, was studied by Fourier Transform Near Infrared (FT-NIR) spectroscopy. Skin reflectance spectra were measured with a fibre-optic probe in four locations (sites): hand, arm, leg and foot. For reference, a group of 28 healthy controls was also measured, Multivariate analysis of the NIR spectra obtained shows a high potential for classification and discrimination of the skin conditions. Valuable indications for future experiments can be observed.

Keywords

FT-NIR; fibre-optic probe; PCA; PLS-DA; skin changes; diabetes

Published in

Journal of Near Infrared Spectroscopy
2000, volume: 8, number: 4, pages: 217-227
Publisher: N I R PUBLICATIONS

SLU Authors

• Geladi, Paul

  • Umeå University

• Nyström, Josefina

  • Umeå University

UKÄ Subject classification

Other Chemistry Topics

Publication identifier

• DOI: https://doi.org/10.1255/jnirs.282

Permanent link to this page (URI)

https://res.slu.se/id/publ/63168