Short-Term Hemodynamic and Neuroendocrine Effects of Pimobendan and Benazapril in Dogs with Myxomatous Mitral Valve Disease and Congestive Heart Failure

Abstract

Conclusions and Clinical ImportancePimobendan improves short-term cardiac function more than benazepril in dogs with CHF caused by MMVD. Pimobendan treatment enables the heart to work at smaller end-systolic and diastolic dimensions while maintaining adequate forward stroke volume. Some of the treatment responses found in neuroendocrine profile might have therapeutic relevance.

Keywords

Canine; Heart rate; Heart size; Mitral regurgitation; Therapy

Published in

Journal of Veterinary Internal Medicine
2013, volume: 27, number: 6, pages: 1452-1462
Publisher: WILEY-BLACKWELL

SLU Authors

• Häggström, Jens

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Lord, Peter

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Höglund, Katja

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Ljungvall, Ingrid

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

• Kvart, Clarence

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Hansson, Kerstin

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Cardiac and Cardiovascular Systems

Publication identifier

• DOI: https://doi.org/10.1111/jvim.12217

Permanent link to this page (URI)

https://res.slu.se/id/publ/51700