A case report of serological evidence of paramyxoviruses related to Porcine orthorubulavirus in Mexican bats

Abstract

In this report, we showed the presence of antibodies to Porcine orthorubulavirus (PRV) in Mexican bats using a serological approach. A total of 42 bats, belonging to seven different species, were sampled from two different refuges/caves, located near to a pig fattening area where spontaneous outbreaks of PRV had occurred. Analysis by serum-virus neutralizing and immunoperoxidase monolayer assay revealed the presence of antibodies in fifteen out of 42 investigated bats (i.e. 35%), six of them were also positive by Paramyxoviridae family using PCR assay targeting the L gene of paramyxoviruses. This case demonstrates for the first time antibodies detection of this virus in different bats species which is important for our understanding of PRV ecology, evolution and mechanism of cross-species transmission. These findings support the hypothesis that bats could act as an intermediate or natural host for interspecies transmission of certain paramyxoviruses.

Keywords

Porcine orthorubulavirus; Bats; Epidemiology; Inter-species transmission

Published in

Annals of clinical case reports
2022, Volume: 7, number: 1, article number: 2177

SLU Authors

• Cuevas, Julieta Sandra

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    
  • Instituto nacional de investigaciones forestales agrícolas y pecuarias (INIFAP)

• Blomström, Anne-Lie

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Berg, Mikael

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Pathobiology


Publication identifier

DOI: https://doi.org/10.25107/2474-1655.2177

Permanent link to this page (URI)

https://res.slu.se/id/publ/121870