An updated overview of Gypsophila species: Phytochemical and pharmacological investigations

Abstract

Medicinal plants and their consituents play a crucial role in disease prevention and treatment. The genus Gypsophila (Caryophyllaceae family), comprising approximately 150 species of flowering plants, holds significant value in both ornamental and therapeutic fields. Traditional uses in various cultures highlight their potential in treating a range of conditions, such as liver disorders, diabetes, and kidney stones. These resilient plants, known for their delicate blooms and adaptability to diverse environments, are rich in chemical compounds, including non-volatile constituents such as phenolic compounds (e.g., flavonoids), terpenoids, saponins, cyclopeptides, and alkaloids. Additionally, monoterpenes and sesquiterpenes, the primary volatile constituents, exhibit significant insecticidal properties. Gypsophila species show a broad spectrum of pharmacological effects, including hepatoprotective, cytotoxic, anti-diabetic, antioxidant, cytotoxic, anti-inflammatory, diuretic, neuroprotective, and anti-obesity properties. This review underscores the promising therapeutic potential of Gypsophila and advocates for further research, particularly clinical trials, to thoroughly assess their efficacy and safety. By consolidating existing knowledge, it sheds light on the potential of Gypsophila species as valuable resources for human health and underscores the need for continued exploration to uncover novel treatments and interventions.

Keywords

Caryophyllacea; Gypsophila; Pharmacological effects; Phytochemistry; Hepatoprotective; Cytotoxic effects

Published in

Fitoterapia
2024, volume: 179, article number: 106230
Publisher: ELSEVIER

SLU Authors

• Mottaghipisheh, Javad

  • Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Pharmacology and Toxicology
Medicinal Chemistry

Publication identifier

• DOI: https://doi.org/10.1016/j.fitote.2024.106230

Permanent link to this page (URI)

https://res.slu.se/id/publ/132894