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Research article2013Peer reviewedOpen access

The ESR1 gene is associated with risk for canine mammary tumours

Borge, Kajsa Sverdrup; Melin, Malin; Rivera, Patricio; Thoresen, Stein Istre; Webster, Matthew Thomas; Von Euler, Henrik; Lindblad-Toh, Kerstin; Lingaas, Frode

Abstract

Conclusions: The identification of CMT-associated SNPs in ESR1 in two independent datasets suggests that this gene might be involved in CMT development. These findings also support that CMT may serve as a good model for human breast cancer research.

Keywords

Dog; Single nucleotide polymorphism; Allele frequency; Risk; Association; Mammary tumour; Estrogen receptor

Published in

BMC Veterinary Research
2013, volume: 9
Publisher: BIOMED CENTRAL LTD

SLU Authors

Global goals (SDG)

SDG3 Good health and well-being

UKÄ Subject classification

Other Veterinary Science

Publication identifier

  • DOI: https://doi.org/10.1186/1746-6148-9-69

Permanent link to this page (URI)

https://res.slu.se/id/publ/53911