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Research article2013Peer reviewedOpen access

The effects of pulse-delivered inhaled nitric oxide on arterial oxygenation, ventilation-perfusion distribution and plasma endothelin-1 concentration in laterally recumbent isoflurane-anaesthetized horses

Grubb, Tamara; Frendin, Jan; Edner, Anna; Funkquist, Pia; Hedenstierna, Göran; Nyman, Görel

Abstract

Conclusions and Clinical Relevance PiNO delivered in the initial portion of the inspiration effectively relieves hypoxaemia in anaesthetized horses by improving ((V) over dot(A)/(Q) over dot) matching and decreasing ((Q) over dots/(Q) over dott) without affecting ET-1.

Keywords

anaesthesia; endothelin-1; gas exchange; horse; hypoxaemia; MIGET; nitric oxide; (Q) over dots/(Q) over dott; shunt; (V) over dot(A)/(Q) over dot

Published in

Veterinary Anaesthesia and Analgesia
2013, volume: 40, number: 6, pages: E19-E30
Publisher: WILEY-BLACKWELL

SLU Authors

UKÄ Subject classification

Clinical Science
Agricultural Science

Publication identifier

  • DOI: https://doi.org/10.1111/vaa.12037

Permanent link to this page (URI)

https://res.slu.se/id/publ/56198