Swimming activity in zebrafish larvae exposed to veterinary antiparasitic pharmaceuticals

Abstract

Veterinary antiparasitic pharmaceuticals have been detected in surface waters and several of these pharmaceuticals act on the nervous system on the target organisms implying that neurological effects also might be of concern in non-target animals such as fish. We tested if exposure to antiparasitic pharmaceuticals affect swimming activity in 6 days old zebrafish larvae. The results revealed that most pharmaceuticals did not cause any effects in swimming activity. However, larvae exposed to 0.58 mg/L doramectin displayed reduced swimming activity even though they were classified as normal, having no morphological abnormalities.

Keywords

Danio rerio; Embryo; Behavior; Locomotor activity; Neurotoxicity

Published in

Environmental toxicology and pharmacology
2018, volume: 63, pages: 74-77

SLU Authors

• Carlsson, Gunnar

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Pohl, Johannes

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Örn, Stefan

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

Global goals (SDG)

SDG3 Good health and well-being
SDG6 Clean water and sanitation

UKÄ Subject classification

Developmental Biology

Publication identifier

• DOI: https://doi.org/10.1016/j.etap.2018.08.015

Permanent link to this page (URI)

https://res.slu.se/id/publ/96309