Sammanfattning

The origin of eukaryotes is a major open question in evolutionary biology. Multiple hypotheses posit that eukaryotes likely evolved from a syntrophic relationship between an archaeon and an alphaproteobacterium based on H-2 exchange. However, there are no strong indications that modern eukaryotic H-2 metabolism originated from archaea or alphaproteobacteria. Here, we present evidence for the origin of H-2 metabolism genes in eukaryotes from an ancestor of the Anoxychlamydiales-a group of anaerobic chlamydiae, newly described here, from marine sediments. Among Chlamydiae, these bacteria uniquely encode genes for H-2 metabolism and other anaerobiosis-associated pathways. Phylogenetic analyses of several components of H-2 metabolism reveal that Anoxychlamydiales homologs are the closest relatives to eukaryotic sequences. We propose that an ancestor of the Anoxychlamydiales contributed these key genes during the evolution of eukaryotes, supporting a mosaic evolutionary origin of eukaryotic metabolism.

Publicerad i

Science Advances
2020, Volym: 6, nummer: 35, artikelnummer: eabb7258
Utgivare: AMER ASSOC ADVANCEMENT SCIENCE

SLU författare

• Tamarit Chuliá, Daniel

  • Institutionen för vatten och miljö, Sveriges lantbruksuniversitet
    
  • Uppsala universitet
  • Wageningen University & Research

UKÄ forskningsämne

Evolutionsbiologi


Publikationens identifierare

DOI: https://doi.org/10.1126/sciadv.abb7258

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/107812