Sammanfattning

Testicular histopathology is considered the most sensitive and reliable method to detect the effects of chemicals on sperm production. To carry out a sensitive examination of testicular histopathology and interpret the changes require knowledge of spermatogenic stages. Spermatogenic staging based on acrosome development during spermiogenesis is conventionally performed in animal species routinely used for research and toxicity testing. In contrast, small ruminants, such as sheep and goats, are rarely used as animal models to evaluate toxicity in male reproductive organs. To the best of our knowledge, a comparable spermatogenic staging system in rams has not yet been fully characterised. Hence, this study aimed to adapt the existing spermatogenic staging based on acrosome development in bull testes to fit the seminiferous epithelium cycle of ram testes. The results show that spermatogenic staging based on acrosome development in bull testes can, with slight modifications, be efficiently used for the staging of ram testes.

Nyckelord

ram; spermatogenesis; staging; acrosome development; spermiogenesis

Publicerad i

Journal of toxicologic pathology
2021, Volym: 34, nummer: 4, sidor: 331-338
Utgivare: JAPANESE SOC TOXICOLOGIC PATHOLOGY

SLU författare

• Spörndly-Nees, Ellinor

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Patobiologi


Publikationens identifierare

DOI: https://doi.org/10.1293/tox.2021-0025

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/114268