Sammanfattning

AA amyloidosis can be transmitted experimentally in several mammalian and avian species as well as spontaneously between captive animals, even by oral intake of amyloid seeds. Amyloid seeding can cross species boundaries, and fibrils of one kind of amyloid protein may also seed other types. Here we show that meat from Swedish and Italian cattle for consumption by humans often contains AA amyloid and that bovine AA fibrils efficiently cross-seed human amyloid beta peptide, associated with Alzheimer's disease.

Publicerad i

Scientific Reports
2021, Volym: 11, nummer: 1, artikelnummer: 21069
Utgivare: NATURE PORTFOLIO

SLU författare

• Rising, Anna

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    
  • Karolinska institutet

UKÄ forskningsämne

Biokemi och molekylärbiologi
Neurovetenskaper


Publikationens identifierare

DOI: https://doi.org/10.1038/s41598-021-00588-w

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/114384