Sammanfattning

Computational modeling was applied to investigate how cortical neurodynamics may depend on network connectivity. In particular, we study effects of pruning of cortical networks, which may be related to the onset of different mental disorders. In addition, we study changes in EEG pattern of depressed patients, following ECT (electroconvulsive therapy). The aim is to gain a better understanding of the neural mechanisms responsible for these changes, which include phase shifts in the EEG dynamics. This understanding is intended to provide clinical guidance, predicting ECT dose and response in depressed patients. Finally, we discuss the relevance of these results to clinical and experimental neuroscience and speculate on a link between neural instability and mental disorders

Nyckelord

Neurodynamics; network connectivity; EEG; ECT; pruning; mental disorder; computational models

Publicerad i

Titel: Proceedings of ICCN'07
Utgivare: Springer

Konferens

1st International Conference on Cognitive Neurodynamics 2007

SLU författare

• Liljenström, Hans

  • Institutionen för energi och teknik, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Livsmedelsvetenskap


Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/16407