Sammanfattning

Spontaneous mammary tumours are most frequently seen (apart from rodents) in women, female dogs and cats. The mammary gland is the most commonly affected organ for tumours in women and in female dogs. The mammary gland has a similar histology in the different species whereas the number of glands differs as well as the number of interlobular ducts that reach the nipple/teat. The parenchymatous tissue is composed of alveoli that turn into interlobular ducts. The whole ductal tree is outlined by a two-layered epithelium with the luminal epithelial cells adjacent to the lumen and the more sparse myoepithelial cells peripherally located to these. Different proteins such as growth factors regulate the mammary gland, as they do for all tissues in the body. In addition, sex hormones regulate the biology of the mammary gland. Oestrogen has the most pronounced effect on duct growth whereas progesterone promotes growth of the alveoli.

Nyckelord

breast; sarcoma; genesis; canine

Publicerad i

Journal of Dairy Research
2005, Volym: 72, nummer: SI, sidor: 90-97

SLU författare

• Hellmén, Eva

  • Institutionen för anatomi och fysiologi, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Veterinärmedicin
Husdjursvetenskap


Publikationens identifierare

DOI: https://doi.org/10.1017/S002202990500124X

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/24078