Sammanfattning

Dogs can be grouped into two distinct types of breed based on the predisposition to chondrodystrophy, namely, non-chondrodystrophic (NCD) and chondrodystrophic (CD). In addition to a different process of endochondral ossification, NCD and CD breeds have different characteristics of intravertebral disc (IVD) degeneration and IVD degenerative diseases. The anatomy, physiology, histopathology, and biochemical and biomechanical characteristics of the healthy and degenerated IVD are discussed in the first part of this two-part review. This second part describes the similarities and differences in the histopathological and biochemical characteristics of IVD degeneration in CD and NCD canine breeds and discusses relevant aetiological factors of IVD degeneration. (C) 2012 Elsevier Ltd. All rights reserved.

Nyckelord

Intervertebral disc; Degeneration; Hernia; Dog; Chondrodystrophic; Non-chondrodystrophic; Notochordal cell

Publicerad i

Veterinary Journal
2013, Volym: 195, nummer: 3, sidor: 292-299
Utgivare: ELSEVIER SCI LTD

SLU författare

• Bergknut, Niklas

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

• Hagman, Ragnvi

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

• Lagerstedt, Anne-Sofie

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Neurologi
Klinisk vetenskap
Ortopedi


Publikationens identifierare

DOI: https://doi.org/10.1016/j.tvjl.2012.10.011

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/43825