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Forskningsartikel2011Vetenskapligt granskadÖppen tillgång

Complete genome sequence of Brachyspira intermedia reveals unique genomic features in Brachyspira species and phage-mediated horizontal gene transfer

Håfström, Therese; Jansson, Monica Desiree Seger; Segerman, Bo

Sammanfattning

Conclusions: The accessory gene pool shapes species-specific traits. It is also influenced by reductive genome evolution and horizontal gene transfer. Gene-transfer events can cross both species and genus boundaries and bacteriophages appear to play an important role in this process. A mechanism for horizontal gene transfer appears to be gene translocations leading to remodeling of bacteriophages in combination with broad tropism.

Nyckelord

Brachyspira intermedia; genome comparison; bacteriophages; horizontal gene transfer; AT/GC-skew

Publicerad i

BMC Genomics
2011, Volym: 12, artikelnummer: 395
Utgivare: BIOMED CENTRAL LTD