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Forskningsartikel2015Vetenskapligt granskadÖppen tillgång

Dynamic expression of leukocyte innate immune genes in whole blood from horses with lipopolysaccharide-induced acute systemic inflammation

Vinther, AML; Skovgaard, K; Heegaard, PMH; Andersen, PH

Sammanfattning

Conclusions: This first broad study of gene expressions in blood leukocytes during equine acute LPS-induced systemic inflammation thoroughly characterized a highly regulated and dynamic innate immune response. These results provide new insights into the molecular mechanisms of equine systemic inflammation.

Nyckelord

Baseline expression variability; Cytokines; Endotoxemia; Equine; Gene expression dynamics; Innate immunity; Leukocytes; Lipopolysaccharide; Systemic inflammation; Time course study

Publicerad i

BMC Veterinary Research
2015, Volym: 11, artikelnummer: 134

    UKÄ forskningsämne

    Annan veterinärmedicin

    Publikationens identifierare

    DOI: https://doi.org/10.1186/s12917-015-0450-5

    Permanent länk till denna sida (URI)

    https://res.slu.se/id/publ/68760