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Forskningsartikel2012Vetenskapligt granskadÖppen tillgång

easyRNASeq: a bioconductor package for processing RNA-Seq data

Delhomme, Nicolas; Padioleau, Ismael; Furlong, Eileen E.; Steinmetz, Lars M.

Sammanfattning

Motivation: RNA sequencing is becoming a standard for expression profiling experiments and many tools have been developed in the past few years to analyze RNA-Seq data. Numerous 'Bioconductor' packages are available for next-generation sequencing data loading in R, e. g. ShortRead and Rsamtools as well as to perform differential gene expression analyses, e. g. DESeq and edgeR. However, the processing tasks lying in between these require the precise interplay of many Bioconductor packages, e. g. Biostrings, IRanges or external solutions are to be sought.Results: We developed 'easyRNASeq', an R package that simplifies the processing of RNA sequencing data, hiding the complex interplay of the required packages behind a single functionality.

Publicerad i

Bioinformatics
2012, Volym: 28, nummer: 19, sidor: 2532-2533
Utgivare: OXFORD UNIV PRESS

    UKÄ forskningsämne

    Bioinformatik och systembiologi
    Bioinformatik (beräkningsbiologi)

    Publikationens identifierare

    DOI: https://doi.org/10.1093/bioinformatics/bts477

    Permanent länk till denna sida (URI)

    https://res.slu.se/id/publ/80799