Sammanfattning

The first steps are reported in the development of a new ultrasensitive electrochemical biosensor for detection of Escherichia colt (E. colt) in water. Two gold electrodes in a sandwich flow-cell were modified with E. coli polyclonal antibody and exposed to three different concentrations of E. coll. Electrochemical Impedance Spectroscopy was used in combination with Singular Value Decompostion of the complex numbers to monitor the interactions at the electrode surfaces. A linear regression line in the concentration range 10-1000 CFU*m1(-1) was obtained without use of redox probes or metal nanoparticles for signal amplification.

Publicerad i

Chemometrics and Intelligent Laboratory Systems
2017, Volym: 163, sidor: 49-54
Utgivare: ELSEVIER SCIENCE BV

SLU författare

• Geladi, Paul

  • Institutionen för skogens biomaterial och teknologi, Sveriges lantbruksuniversitet
    
  • Corpus Data & Image Analysis

UKÄ forskningsämne

Analytisk kemi


Publikationens identifierare

DOI: https://doi.org/10.1016/j.chemolab.2016.11.008

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/82740