Sammanfattning

Four dialkylresorcinols (1-4) were isolated from a liquid culture of Pseudomonas sp. Ki19. Compounds 1 and 2, 2-butyl-5-propylresorcinol and 2-hexyl-5-methylresorcinol, respectively, have not previously been isolated from biological sources, whereas 3 and 4, 2-hexyl-5-propylresorcinol (DB-2073) and 2-hexyl-5-pentylresorcinol ( resorstatin), both have been found in biological systems. The compounds inhibited Staphyllococcus aureus at concentrations <= 10 mu g/mL as well as the fungi Aspergillus fumigatus and Fusarium culmorum at 50 mu g/mL. The formation of possible antimicrobial quinone oxidation products was investigated under bioassay conditions, and they were not found to be responsible for the main antimicrobial activity

Publicerad i

Journal of Natural Products
2006, Volym: 69, nummer: 4, sidor: 654-657
Utgivare: AMER CHEMICAL SOC

SLU författare

• Pohanka, Anton

  • Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
    

• Broberg, Anders

  • Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
    

Publikationens identifierare

DOI: https://doi.org/10.1021/np0600595

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/8647