Preliminary study on the relationship between aflatoxin-bovine serum albumin adducts in blood and aflatoxin M1 levels in milk of dairy cows

Sammanfattning

The aflatoxin (AF) albumin adduct is often used as a biomarker for aflatoxin exposure in humans. An ELISA method previously used for aflatoxin serum albumin in human blood was used to analyse bovine serum samples (n = 22) collected from dairy cattle during an aflatoxin mitigation study in Kenya. Albumin adduct data were compared with aflatoxin M-1 (AFM(1)) levels in corresponding milk samples from these cows. The concentration ranged from < LOD to 487.9 pg/mL for AFM(1) and < LOD and 96.3 pg/mg for aflatoxin-albumin. This study indicates that aflatoxin-albumin adducts could be used as a measure of chronic aflatoxin exposure in dairy cattle.

Nyckelord

Aflatoxin-albumin adduct; Biomarker; Aflatoxin M-1; ELISA; Dairy cow

Publicerad i

Mycotoxin Research
2020, volym: 36, nummer: 2, sidor: 207-211
Utgivare: SPRINGER HEIDELBERG

SLU författare

• Lindahl, Johanna

  • International Livestock Research Institute (ILRI)
  • Uppsala universitet

UKÄ forskningsämne

Klinisk vetenskap
Husdjursvetenskap

Publikationens identifierare

• DOI: https://doi.org/10.1007/s12550-019-00383-7

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/105610