Structure-activity relationships for analogues of (Z)-5-decenyl acetate, a sex pheromone component of the turnip moth, Agrotis segetum: Synthesis and conformational analysis

Sammanfattning

Structure-activity relationships for 28 analogues of (Z)-5-decenyl acetate, a sex pheromone component of the turnip moth Agrotis segetum, have been studied.Synthesis and conformational analysis of chain-elongated, chain-shortened, alkyne, alkenyne, diene and cyclic analogues, and configurational isomers are presented.A conformational-energy model for the interaction of a pheromone component with its receptor cell has been developed and tested.The model is shown to correlate measured electrophysiological single-cell activities with conformational energies calculated by the molecular mechanics (MM2/MMP2) method.A biologically active conformation of the natural pheromone component, (Z)-5-decenyl acetate, is suggested.

Publicerad i

Utgivare: Lund University

SLU författare

• Bengtsson, Marie

  • Lunds Universitet

UKÄ forskningsämne

Biokemi
Molekylärbiologi

Publikationens identifierare

• ISBN: 9907128066

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/110609