Kenne, Lennart
- Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
Sammanfattning
The interaction between (-)-epigallocatechin-'3-gallate (EGCG) and beta- or gamma-cyclodextrin (CD), in free solution and bonded to silica beads, has been studied by H-1 HR-MAS NMR spectroscopy. The chromatographic retardation of EGCG on columns packed with CD-silica beads was shown to be due to the interaction of EGCG with the CD ligands because no nonspecific interaction with the silica gel could be observed. EGCG forms a tighter complex with beta-CD than with gamma-CD and NMR data obtained from hydroxy protons together with mm2 calculations suggest that for beta-CD intermolecular hydrogen bonding, in addition to hydrophobic interaction, stabilizes the complex. (c) 2007 Elsevier Ltd. All rights reserved.
Nyckelord
cyclodextrins; epigallocatechin gallate; HR-MAS NMR; silica beads
Publicerad i
Carbohydrate Research
2007, volym: 342, nummer: 6, sidor: 843-850
Utgivare: ELSEVIER SCI LTD
SLU författare
Sandström, Corine
- Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
- Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
Publikationens identifierare
- DOI: https://doi.org/10.1016/j.carres.2007.01.007
Permanent länk till denna sida (URI)
https://res.slu.se/id/publ/14074