Ultrafast, cytocompatible mineralization of calcium phosphate in the formation of stratified nanoshells of artificial spores

Nguyen, Duc Tai; Han, Sang Yeong; Choi, Hyunwoo; Kim, Nayoung; Seisenbaeva, Gulaim A.; Kessler, Vadim G.; Choi, Insung S.

doi:10.1039/d5cc00522a

Forskningsartikel2025Vetenskapligt granskadÖppen tillgång

Ultrafast, cytocompatible mineralization of calcium phosphate in the formation of stratified nanoshells of artificial spores

Nguyen, Duc Tai; Han, Sang Yeong; Choi, Hyunwoo; Kim, Nayoung; Seisenbaeva, Gulaim A.; Kessler, Vadim G.; Choi, Insung S.

Sammanfattning

Spatially controlled confinement of catalytic enzymes within nanoshells holds substantial potential for applications in bioreactors, synthetic cells, and artificial spores. The utilization of amorphous calcium phosphate (CaP) precursors enables the extremely rapid (<5 seconds) construction of thick (similar to 400 nm) CaP nanoshells, stratified with distinct enzymes, on various tannic acid-primed substrates. Saccharomyces cerevisiae cells are nanoencapsulated with enzyme-embedded, multilayered CaP nanoshells in a cytocompatible manner, providing an advanced chemical tool for interfacing living cells with functional entities in a spatially controlled configuration.

Publicerad i

Chemical Communications
2025, volym: 61, nummer: 37, sidor: 6771-6774
Utgivare: ROYAL SOC CHEMISTRY

SLU författare

Seisenbaeva, Gulaim
- Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet
Kessler, Vadim
- Institutionen för molekylära vetenskaper, Sveriges lantbruksuniversitet

UKÄ forskningsämne

Oorganisk kemi

Publikationens identifierare

DOI: https://doi.org/10.1039/d5cc00522a

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/141629