Wiberg, Karin
- Institutionen för vatten och miljö, Sveriges lantbruksuniversitet
Non-target and suspect mass spectrometry screening (NTS and SS) are increasingly used to detect a broad range of chemical contaminants in exposed matrices. However, differences in expectations between regulatory authorities and academic researchers can limit the effective use of the information obtained by such commissioned studies. This report summarizes the outcomes of a 2024 workshop organized by the Swedish Toxicological Council that aimed to improve collaboration and align expectations between regulators and researchers involved in NTS and SS projects.
Participants from regulatory agencies, research institutions, and other stakeholders identified key challenges and recommendations across four stages of commissioned studies: project design, study implementation, reporting and interpretation of results, and post-project communication. Early and transparent discussions were highlighted as essential to clearly define regulatory questions, establish realistic expectations, and determine whether targeted analysis, SS or non-target screening, alternatively a combination of them, is the most appropriate approach.
The workshop also emphasized the importance of continuous dialogue during project execution, robust quality assurance procedures, transparent reporting of confidence levels and detection limits, and the strategic archiving of analytical data for future retrospective analysis. Strengthening communication and aligning expectations were identified as key steps to enhance the regulatory value of NTS and SS in environmental monitoring and chemical risk management.
Non-target screening; Suspect screening; High Resolution Mass Spectrometry; HRMS; Regulatory – academic collaboration
Rapport / Sveriges lantbruksuniversitet, Institutionen för vatten och miljö
2026, nummer: 2025:14
Utgivare: Department of Aquatic Sciences and Assessment, Swedish University of Agricultural Sciences
Miljövetenskap
Analytisk kemi
https://res.slu.se/id/publ/146647