Häggström, Jens
- Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
Sammanfattning
Background: Systolic dysfunction associated with chronic mitral valve insufficiency (CMVI) has been demonstrated in experimental animal models and large breed (LB) dogs but has been reported as an uncommon finding in small breed (SB) dogs with naturally occurring disease. It has been Suggested the myocardial failure could be, in part, because of an insufficient increase in left ventricular mass. Hypothesis: To test if SB and LB dogs with CMVI and moderate heart failure have systolic dysfunction and if they have adequate eccentric hypertrophy. Animals: Data from 38 SB and 18 LB dogs affected with CMVI were compared retrospectively with results from 2 groups of normal dogs (17 SB and 32 LB) Methods: Systolic function was investigated echocardiographically by using percentage fractional shortening (FS), the ratio between observed and expected end-systolic diameter (ESD/ESDe), and end-systolic Volume index (ESVI). Left ventricular hypertrophy was estimated by using the ratio between the thickness of the left ventricular free wall and the radius in diastole (h/R). Results: Both affected SB and LB dogs had a significantly increased FS and ESVI (ESVI, SB 45.6 + 8.04 versus 40.06 + 8.9, P
Publicerad i
Journal of Veterinary Internal Medicine
2007, volym: 21, nummer: 1, sidor: 61-67
Utgivare: AMER COLL VETERINARY INTERNAL MEDICINE
SLU författare
UKÄ forskningsämne
Veterinärmedicin
Husdjursvetenskap
Publikationens identifierare
- DOI: https://doi.org/10.1892/0891-6640(2007)21[61:DSFAIH]2.0.CO;2
Permanent länk till denna sida (URI)
https://res.slu.se/id/publ/16365