Grip, Stefan
- Gemensamma verksamhetsstödet, Sveriges lantbruksuniversitet
Sammanfattning
JNK interacting Protein 1 (JIP-1) is a pivotal scaffolding protein in the JNK signalling pathway. Its expression pattern in murine tissue indicates that JIP-1 has a role in the regulation of different cellular events. By examining the JIP-1 expression in transgenic mice that were heterozygous for a functional insulin-like growth factor II (igf-2) gene, it was possible to show that an abrogated igf-2 expression was followed by a decreased transcription of the JIP-l gene. This pattern was consistent through different litters, which suggests that the up- or down-regulation of JIP-1 may well be part of the intracellular mediation of IGF II induced messages
Publicerad i
In Vivo
2004, volym: 18, nummer: 5, sidor: 643-647
Utgivare: INT INST ANTICANCER RESEARCH
SLU författare
Rising, Anna
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
Engström, Wilhelm
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
UKÄ forskningsämne
Husdjursvetenskap
Veterinärmedicin
Permanent länk till denna sida (URI)
https://res.slu.se/id/publ/21935