Ljungvall, Karl
- Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
Sammanfattning
Octylphenol is an industrial chemical with estrogenic effects both in vitro and in vivo. In this study the effects of short-term intramuscular exposure to 0.1 mg/kg of body weight and 1.0 mg/kg of body weight in early gestation were evaluated in pregnant sows with respect to reproductive parameters in the newborn male piglets, as compared with male piglets from unexposed control sows. The male piglets were examined immediately after birth with respect to the macroscopic appearance of the reproductive organs and testosterone concentration in serum. It was not possible to identify any estrogenic effects in the newborn male piglets. However, in the sows exposed at the highest level of octylphenol, there was an increased number of stillborn piglets and an increased proportion of sows with stillborn piglets in the litter (P < 0.05). This was an unexpected finding which has not been reported previously. (C) 2012 Elsevier Inc. All rights reserved.
Nyckelord
Endocrine disruption; Pig; Octylphenol; Stillbirth; Male
Publicerad i
Theriogenology
2012, volym: 78, nummer: 7, sidor: 1494-1499
Utgivare: ELSEVIER SCIENCE INC
SLU författare
Norrgren, Leif
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
Magnusson, Ulf
- Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
- Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
UKÄ forskningsämne
Övrig annan medicin och hälsovetenskap
Publikationens identifierare
- DOI: https://doi.org/10.1016/j.theriogenology.2012.06.028
Permanent länk till denna sida (URI)
https://res.slu.se/id/publ/42992