Ström Holst, Bodil
- Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
Sammanfattning
Immunoreaction for TNF was found in all samples used. In the dog testis, TNF immunoexpression was limited to the seminiferous tubules, where late round spermatids (SPD) showed weak intensity of immunostaining, while elongating and elongated SPD evidenced moderate and the residual bodies a strong intensity. In the epididymis, a gradual progressive increase of TNF immunolabelling was found throughout the epididymal regions, ranging from a weak intensity at the caput epididymis to a moderate intensity at the cauda. TNF immunolabelling was found in mature SPZ during the epididymal transit and also in freshly ejaculated SPZ, which showed a strong midpiece immunolabelling. Data presented here provide important information on expression of TNF in spermatozoa, which is acquired by the SPZ during their formation at the testis. It further provides the basis for subsequent studies on the physiological importance of cytokines in sperm function. (c) 2012 Elsevier Inc. All rights reserved.
Nyckelord
Tumor necrosis factor-alpha; Spermatogenesis; Testis; Spermatozoa; Dog
Publicerad i
Theriogenology
2012, volym: 77, nummer: 8, sidor: 1540-1548
Utgivare: ELSEVIER SCIENCE INC
SLU författare
UKÄ forskningsämne
Patobiologi
Publikationens identifierare
- DOI: https://doi.org/10.1016/j.theriogenology.2011.11.021
Permanent länk till denna sida (URI)
https://res.slu.se/id/publ/45618