The emergence of genotypes 3 and 4 hepatitis E virus in swine and humans: a phylogenetic perspective

Sammanfattning

To investigate whether there is any phylogenetic evidence to support the hypothesis that swine is the natural host of HEV genotypes 3 and 4, Bayesian analysis of 80 full-length genomic sequences of HEV was performed. The results showed that the strains of genotypes 3 and 4 from swine are paraphyletic with regard to strains of human origin, which are thus phylogenetically nested among the swine strains. Recognition of HEV genotypes 3 and 4 as viruses from swine or swine HEV can provide an evolutionary explanation to the observation of cross-species infection by genotypes 3 and 4 HEV.

Nyckelord

HEV; Evolution; Molecular epidemiology; Phylogeny

Publicerad i

Archives of Virology
2011, volym: 156, nummer: 1, sidor: 121-124
Utgivare: SPRINGER WIEN

SLU författare

• Xia, Hongyan

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• Belak, Sandor

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• Liu, Lihong

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

Globala målen (SDG)

SDG3 God hälsa och välbefinnande

UKÄ forskningsämne

Veterinärmedicin
Husdjursvetenskap

Publikationens identifierare

• DOI: https://doi.org/10.1007/s00705-010-0818-6

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/47508