Associations between cardiac pathology and clinical, echocardiographic and electrocardiographic findings in dogs with chronic congestive heart failure

Falk, Torkel; Jonsson, Lennart; Olsen, Lisbeth H.; Tarnow, Inge; Pedersen, Henrik D.

doi:10.1016/j.tvjl.2010.04.016

Sammanfattning

Arterial narrowing significantly correlated with fibrosis (P < 0.0001) and with fractional shortening, an indicator of systolic function (P = 0.002). The grade of fibrosis was associated with shorter survival time (P = 0.002), and the papillary muscle fibrosis score tended to correlate with proximal isovelocity surface area radius (P = 0.03). Data from this study lend support to the hypothesis that naturally occurring canine CHF is affected by several factors such as MMVD, myocardial atrophy and fibrosis, and by arteriosclerosis. Further, more extensive research will be required to establish cause-effect relationships between these cardiac lesions and the pathophysiology of CHF in dogs. (C) 2010 Published by Elsevier Ltd.

Nyckelord

Arteriosclerosis; Myxomatous mitral valve degeneration; Canine chronic congestive heart failure; Cardiac pathology; Biomarkers

Publicerad i

Veterinary Journal
2010, volym: 185, nummer: 1, sidor: 68-74
Utgivare: ELSEVIER SCI LTD

SLU författare

Jönsson, Lennart
- Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet

UKÄ forskningsämne

Klinisk vetenskap
Patobiologi

Publikationens identifierare

DOI: https://doi.org/10.1016/j.tvjl.2010.04.016

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/48055