C1q Inhibits Immune Complex-Induced Interferon-alpha Production in Plasmacytoid Dendritic Cells A Novel Link Between C1q Deficiency and Systemic Lupus Erythematosus Pathogenesis

Abstract

Conclusion. Our findings contribute to the understanding of why C1q deficiency is such a strong risk factor for SLE and suggest an explanation for the up-regulation of the type I IFN system seen in SLE patients.

Published in

Arthritis and Rheumatism
2009, volume: 60, number: 10, pages: 3081-3090
Publisher: WILEY-LISS

SLU Authors

• Alm, Gunnar

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Animal and Dairy Science
Veterinary Science

Publication identifier

• DOI: https://doi.org/10.1002/art.24852

Permanent link to this page (URI)

https://res.slu.se/id/publ/49296