C1q Inhibits Immune Complex-Induced Interferon-alpha Production in Plasmacytoid Dendritic Cells A Novel Link Between C1q Deficiency and Systemic Lupus Erythematosus Pathogenesis

Sammanfattning

Conclusion. Our findings contribute to the understanding of why C1q deficiency is such a strong risk factor for SLE and suggest an explanation for the up-regulation of the type I IFN system seen in SLE patients.

Publicerad i

Arthritis and Rheumatism
2009, volym: 60, nummer: 10, sidor: 3081-3090
Utgivare: WILEY-LISS

SLU författare

• Alm, Gunnar

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Husdjursvetenskap
Veterinärmedicin

Publikationens identifierare

• DOI: https://doi.org/10.1002/art.24852

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/49296