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Sammanfattning

Conclusions: SRIs have highly variable effects on plasma oxytocin between individuals. The associations between baseline oxytocin and OCD severity and between oxytocin changes and treatment response support the notions that oxytocin is involved in OCD pathophysiology, and that the anti-obsessive effects of SRIs are partly exerted through oxytocinergic mechanisms.

Nyckelord

Obsessive-compulsive disorder; Oxytocin/plasma; Serotonin; Serotonin uptake inhibitors; Treatment response; Randomized controlled trial; Autism spectrum disorder; Placebo response

Publicerad i

BMC Psychiatry
2013, volym: 13
Utgivare: BIOMED CENTRAL LTD

SLU författare

UKÄ forskningsämne

Psykiatri

Publikationens identifierare

  • DOI: https://doi.org/10.1186/1471-244X-13-344

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/55284