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Sammanfattning

Polyamines (PAs) have been considered as important molecules for survival. However, evidence reinforces that PAs are also implicated, directly or indirectly, in pathways regulating programmed cell death (PCD). Direct correlation of PAs with cell death refers to their association with particular biological processes, and their physical contact with molecules or structures involved in cell death. Indirectly, PAs regulate PCD through their metabolic derivatives, such as catabolic and interconversion products. Cytotoxic products of PA metabolism are involved in PCD cascades, whereas it remains largely elusive how PAs directly control pathways leading to PCD. In this review, we present and compare advances in PA-dependent PCD in animals and plants.

Nyckelord

Apoptosis; autophagy; cell cycle; cell death; development; oxidases; oxidative stress; polyamines; programmed cell death; spermidine

Publicerad i

Journal of Experimental Botany
2014, volym: 65, nummer: 5, sidor: 1285-1296
Utgivare: OXFORD UNIV PRESS

SLU författare

Associerade SLU-program

SLU Nätverk växtskydd

UKÄ forskningsämne

Utvecklingsbiologi
Biokemi
Molekylärbiologi

Publikationens identifierare

  • DOI: https://doi.org/10.1093/jxb/ert373

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/57530