Studies of the Genetic Background of a Teat Defect in Pigs Born in Germany and Sweden

Abstract

To improve the understanding of the genetics underlying the inverted teat defect in pigs, we combined studies from Germany and Sweden. Based on a linkage study in Germany which revealed highly significant loci in an experimental population, confirmation of regions was attempted using commercial animals. A genome-wide association study on commercial pigs was also conducted in Sweden. Since both datasets of commercial pigs had a relatively low number of samples, we tested if microsatellite and data of SNP arrays have, in a combined analysis, enough power to validate loci with a higher reliability. We combined microsatellite data and haplotypes and verified associated alleles on chromosomes 1, 4, 6, 11, 14 and 18. Approaches like these present an opportunity to re-use old datasets and to increase the power of recent association studies when samples or further funding are not available.

Published in

Title: Proceedings of the 10th World Congress of Genetics Applied to Livestock Production
Publisher: WCGALP

SLU Authors

• Jonas, Elisabeth

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Chalkias, Helena

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• Lindgren, Gabriella

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

• de Koning, Dirk-Jan

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Genetics and Breeding in Agricultural Sciences

Permanent link to this page (URI)

https://res.slu.se/id/publ/63364