Studies of the Genetic Background of a Teat Defect in Pigs Born in Germany and Sweden

Sammanfattning

To improve the understanding of the genetics underlying the inverted teat defect in pigs, we combined studies from Germany and Sweden. Based on a linkage study in Germany which revealed highly significant loci in an experimental population, confirmation of regions was attempted using commercial animals. A genome-wide association study on commercial pigs was also conducted in Sweden. Since both datasets of commercial pigs had a relatively low number of samples, we tested if microsatellite and data of SNP arrays have, in a combined analysis, enough power to validate loci with a higher reliability. We combined microsatellite data and haplotypes and verified associated alleles on chromosomes 1, 4, 6, 11, 14 and 18. Approaches like these present an opportunity to re-use old datasets and to increase the power of recent association studies when samples or further funding are not available.

Publicerad i

Titel: Proceedings of the 10th World Congress of Genetics Applied to Livestock Production
Utgivare: WCGALP

SLU författare

• Jonas, Elisabeth

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• Chalkias, Helena

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• Lindgren, Gabriella

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• de Koning, Dirk-Jan

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Genetik och förädling inom lantbruksvetenskap

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/63364