ASIP and MC1R mutations causing black coat colour in five Swedish sheep breeds

Sammanfattning

Black coat colour in sheep can be determined by the recessive black allele (Aa) in Agouti signaling protein (ASIP) and the dominant black allele (ED) in Melanocortin receptor 1 (MC1R). Aa is a 5 bp deletion (D5) or a mutation (g.5172T>A), and ED is attributed to two mutations; c.218T>A and c.361G>A. ASIP and MC1R coding regions were sequenced in 26 black and 21 white Swedish sheep from Gute, Finewool, Klövsjö, Roslags and Värmlands breeds. Three combinations of D5 and g.5172T>A, where one or both of the mutations were homozygous, were only found in black sheep. The only wildtype animal was white with the remaining sheep, 10 black and 20 white, heterozygous in one or both of the mutations. Animals homozygous or heterozygous for mutations c.218T>A and c.361G>A were black Finewool sheep. Seven black individuals were not black due to Aa or ED.

Publicerad i

Titel: Proceedings of the 10th World Congress of Genetics Applied to Livestock Production
Utgivare: WCGALP

Konferens

10th World Congress of Genetics Applied to Livestock Production

SLU författare

• Rochus, Christina

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    
  • Institut national de la recherche agronomique (INRA)
  • ParisTech Institut des Sciences et Technologies

• Mikko, Sofia

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• Näsholm, Anna

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

• Johansson, Anna Maria

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Genetik och förädling inom lantbruksvetenskap

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/63389