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Sammanfattning

Immunoglobulin A deficiency (IgAD) is the most common primary immunodeficiency in both humans and selected breeds of domestic dogs. In both species, IgAD is associated with recurrent infections and immune mediated diseases. Previous results imply that IgAD is also common in the wild ancestor of domestic dogs, the gray wolf. Here, we report that serum IgA concentrations are significantly different in Scandinavian and Canadian wolves (p =3.252e-15) with an increased prevalence for IgAD in Scandinavian wolves (60%), which is as high as those found in high-risk dog breeds. (C) 2014 Elsevier Ltd. All rights reserved.

Nyckelord

Serum IgA concentrations; IgA deficiency; Dog; Wolf

Publicerad i

Developmental and Comparative Immunology
2015, volym: 50, nummer: 1, sidor: 26-28

SLU författare

UKÄ forskningsämne

Skogsvetenskap
Annan veterinärmedicin
Ekologi

Publikationens identifierare

  • DOI: https://doi.org/10.1016/j.dci.2014.12.009

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/63692