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Sammanfattning

This paper considers how to detect influential observations in crossover models with random individual effects. Two influence measures, the delta-beta influence and variance-ratio influence, are utilized as tools to evaluate the influence of the model on the estimates of mean and variance parameters with respect to case-weighted perturbations, which are introduced to the model for studying the ‘influence’ of cases. The paper provides explicit expressions of the delta-beta and variance-ratio influences for the general two-treatment balanced crossover models when the proposed decompositions for the perturbed models hold. The influence measures for each parameter turn out to be closed-form functions of orthogonal projections of specific residuals in the unperturbed model.

Nyckelord

delta-beta influence; explicit maximum likelihood estimate; mixed linear model; multiple-period crossover design; perturbation scheme

Publicerad i

Mathematical Methods of Statistics
2015, volym: 24, nummer: 1, sidor: 16-36

SLU författare

UKÄ forskningsämne

Sannolikhetsteori och statistik

Publikationens identifierare

  • DOI: https://doi.org/10.3103/S1066530715010020

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/66438