Dynamic expression of leukocyte innate immune genes in whole blood from horses with lipopolysaccharide-induced acute systemic inflammation

Abstract

Conclusions: This first broad study of gene expressions in blood leukocytes during equine acute LPS-induced systemic inflammation thoroughly characterized a highly regulated and dynamic innate immune response. These results provide new insights into the molecular mechanisms of equine systemic inflammation.

Keywords

Baseline expression variability; Cytokines; Endotoxemia; Equine; Gene expression dynamics; Innate immunity; Leukocytes; Lipopolysaccharide; Systemic inflammation; Time course study

Published in

BMC Veterinary Research
2015, volume: 11, article number: 134

SLU Authors

• Haubro Andersen, Pia

  • Department of Clinical Sciences, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Other Veterinary Science

Publication identifier

• DOI: https://doi.org/10.1186/s12917-015-0450-5

Permanent link to this page (URI)

https://res.slu.se/id/publ/68760