Dynamic expression of leukocyte innate immune genes in whole blood from horses with lipopolysaccharide-induced acute systemic inflammation

Sammanfattning

Conclusions: This first broad study of gene expressions in blood leukocytes during equine acute LPS-induced systemic inflammation thoroughly characterized a highly regulated and dynamic innate immune response. These results provide new insights into the molecular mechanisms of equine systemic inflammation.

Nyckelord

Baseline expression variability; Cytokines; Endotoxemia; Equine; Gene expression dynamics; Innate immunity; Leukocytes; Lipopolysaccharide; Systemic inflammation; Time course study

Publicerad i

BMC Veterinary Research
2015, volym: 11, artikelnummer: 134

SLU författare

• Haubro Andersen, Pia

  • Institutionen för kliniska vetenskaper, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Annan veterinärmedicin

Publikationens identifierare

• DOI: https://doi.org/10.1186/s12917-015-0450-5

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/68760