The Polycomb Group Protein Regulatory Network

Abstract

Correct expression of specific sets of genes in time and space ensures the establishment and maintenance of cell identity, which is required for proper development of multicellular organisms. Polycomb and Trithorax group proteins form multisubunit complexes that antagonistically act in epigenetic gene repression and activation, respectively. The traditional view of Polycomb repressive complexes (PRCs) as executors of long-lasting and stable gene repression is being extended by evidence of flexible repression in response to developmental and environmental cues, increasing the complexity of mechanisms that ensure selective and properly timed PRC targeting and release of Polycomb repression. Here, we review advances in understanding of the composition, mechanisms of targeting, and function of plant PRCs and discuss the parallels and differences between plant and animal models.

Keywords

Polycomb repressive complex; epigenetics; gene repression; plant development; Trithorax

Published in

Annual Review of Plant Biology
2015, volume: 66, pages: 269-296
Publisher: ANNUAL REVIEWS, 4139 EL CAMINO WAY, PO BOX 10139, PALO ALTO, CA 94303-0897 USA

SLU Authors

• Mozgova, Iva

  • Department of Plant Biology, Swedish University of Agricultural Sciences
    

• Hennig, Lars

  • Department of Plant Biology, Swedish University of Agricultural Sciences
    

UKÄ Subject classification

Developmental Biology
Evolutionary Biology

Publication identifier

• DOI: https://doi.org/10.1146/annurev-arplant-043014-115627

Permanent link to this page (URI)

https://res.slu.se/id/publ/72374