Association analysis of KIT, MITF, and PAX3 variants with white markings in Spanish horses

Abstract

Several variants in the KIT, PAX3 and MITF genes have previously been associated with white markings in horses. In this study, we examined eight variants of these genes in 70 Menorca Purebred horses (PRMe, only black solid-coloured horses) and 70 Spanish Purebred horses (PRE, different coat colour patterns) that were scored for the extent of white markings. A maximum-likelihood chi-square test, logistic regression model and ridge regression analyses showed that a missense mutation (p.Arg682His) in KIT was associated with white facial markings (P

Keywords

Menorca Purebred; phenotypic variance; Purebred; SNP; white spotting

Published in

Animal Genetics
2017, volume: 48, number: 3, pages: 349-352
Publisher: WILEY

SLU Authors

• Andersson, Leif

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    
  • Texas A&M University
  • Uppsala University

UKÄ Subject classification

Genetics and Breeding in Agricultural Sciences

Publication identifier

• DOI: https://doi.org/10.1111/age.12528

Permanent link to this page (URI)

https://res.slu.se/id/publ/82662