Association analysis of KIT, MITF, and PAX3 variants with white markings in Spanish horses

Sammanfattning

Several variants in the KIT, PAX3 and MITF genes have previously been associated with white markings in horses. In this study, we examined eight variants of these genes in 70 Menorca Purebred horses (PRMe, only black solid-coloured horses) and 70 Spanish Purebred horses (PRE, different coat colour patterns) that were scored for the extent of white markings. A maximum-likelihood chi-square test, logistic regression model and ridge regression analyses showed that a missense mutation (p.Arg682His) in KIT was associated with white facial markings (P

Nyckelord

Menorca Purebred; phenotypic variance; Purebred; SNP; white spotting

Publicerad i

Animal Genetics
2017, volym: 48, nummer: 3, sidor: 349-352
Utgivare: WILEY

SLU författare

• Andersson, Leif

  • Institutionen för husdjurens biovetenskaper, Sveriges lantbruksuniversitet
    
  • Texas A&M University
  • Uppsala universitet

UKÄ forskningsämne

Genetik och förädling inom lantbruksvetenskap

Publikationens identifierare

• DOI: https://doi.org/10.1111/age.12528

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/82662