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Abstract

A new high-affinity thyroid hormone antagonist 6 with druglike properties was designed and synthesized. The compound behaved as an antagonist in a cell transactivation assay, and in a first in vivo experiment in rats.

Published in

Journal of Medicinal Chemistry
2006, volume: 49, number: 23, pages: 6635-6637
Publisher: AMER CHEMICAL SOC

SLU Authors

UKÄ Subject classification

Organic Chemistry

Publication identifier

  • DOI: https://doi.org/10.1021/jm060521i

Permanent link to this page (URI)

https://res.slu.se/id/publ/83871