Auxin minimum triggers the developmental switch from cell division to cell differentiation in the Arabidopsis root

Sammanfattning

In multicellular organisms, a stringent control of the transition between cell division and differentiation is crucial for correct tissue and organ development. In the Arabidopsis root, the boundary between dividing and differentiating cells is positioned by the antagonistic interaction of the hormones auxin and cytokinin. Cytokinin affects polar auxin transport, but how this impacts the positional information required to establish this tissue boundary, is still unknown. By combining computational modeling with molecular genetics, we show that boundary formation is dependent on cytokinin's control on auxin polar transport and degradation. The regulation of both processes shapes the auxin profile in a welldefined auxin minimum. This auxin minimum positions the boundary between dividing and differentiating cells, acting as a trigger for this developmental transition, thus controlling meristem size.

Nyckelord

plant hormones; cell differentiation; root meristem; computational modeling

Publicerad i

Proceedings of the National Academy of Sciences of the United States of America
2017, volym: 114, nummer: 36, sidor: E7641-E7649
Utgivare: NATL ACAD SCIENCES

SLU författare

• Ljung, Karin

  • Institutionen för skoglig genetik och växtfysiologi, Sveriges lantbruksuniversitet
    

UKÄ forskningsämne

Bioinformatik och beräkningsbiologi (Metodutveckling under 10203)

Publikationens identifierare

• DOI: https://doi.org/10.1073/pnas.1705833114

Permanent länk till denna sida (URI)

https://res.slu.se/id/publ/94089