Genetics and Genomics of Social Behavior in a Chicken Model

Abstract

The identification of genes affecting sociality can give insights into the maintenance and development of sociality and personality. In this study, we used the combination of an advanced intercross between wild and domestic chickens with a combined QTL and eQTL genetical genomics approach to identify genes for social reinstatement, a social and anxiety-related behavior. A total of 24 social reinstatement QTL were identified and overlaid with over 600 eQTL obtained from the same birds using hypothalamic tissue. Correlations between overlapping QTL and eQTL indicated 5 strong candidate genes, with the gene TTRAP being strongly significantly correlated with multiple aspects of social reinstatement behavior, as well as possessing a highly significant eQTL.

Keywords

behavior; eQTL; QTL; sociality

Published in

Genetics
2018, volume: 209, number: 1, pages: 209-221
Publisher: Genetics

SLU Authors

• Johnsson, Martin

  • Department of Animal Biosciences, Swedish University of Agricultural Sciences
    
  • Linköping University
  • University of Edinburgh

• Jensen, Per

  • Linköping University

UKÄ Subject classification

Genetics

Publication identifier

• DOI: https://doi.org/10.1534/genetics.118.300810

Permanent link to this page (URI)

https://res.slu.se/id/publ/94335